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See related permethrin information
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| Topical/Cutaneous
Head pediculosis
Adult: Apply 30-60 ml of 1% lotion (cream rinse) to washed and towel-dried hair and allow to remain for 10 min. Rinse with water. Treatment may be repeated after 7-10 days if lice or nits are detected in hair-scalp junctions.
Topical/Cutaneous
Scabies
Adult: Apply a thin layer of 5% cream into all skin surfaces from the neck to toes. Wash off after 8-14 hr. 30 g of cream is usually sufficient for an average adult.
Topical/Cutaneous
Pediculosis pubis
Adult: Apply sufficient amount of 1% lotion (cream rinse) or 5% cream to thoroughly saturate the pubic area. Allow to remain for 10 min and then rinse with water. |
| Hypersensitivity. |
| Avoid contact with eyes and mucous membranes. Cross-sensitivity may occur with ragweed or chrysanthemums. History of asthma. Pregnancy and lactation. |
| Mild and transient burning, stinging, pruritus, erythema, tingling, numbness, rash; difficulty in breathing; phototoxic or photosensitisation reactions.
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| | Category B: Either animal-reproduction studies
have not demonstrated a foetal risk but there are no
controlled studies in pregnant women or animal-reproduction studies have shown
an adverse effect (other than a decrease in fertility) that was not confirmed in
controlled studies in women in the 1st trimester (and there is no
evidence of a risk in later trimesters).
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| Topical/Cutaneous: Cream: Store at 15-25°C (59-77°F). Lotion (Cream rinse): Store at 15-25°C (59-77°F) or at 20-25°C (68-77°F). |
| Permethrin is a pyrethroid pediculocide and scabicide. It causes paralysis and death of the pest by inhibiting sodium ion influx through nerve cell membrane channels delaying repolarisation.
Absorption: Small amounts absorbed systemically (topical).
Metabolism: Hepatic via ester hydrolysis; converted to inactive metabolites.
Excretion: Via urine |
| Topical Antifungals & Antiparasites |
| P03AC04 - permethrin; Belongs to the class of pyrethrines, including synthetic compounds used as ectoparasiticides.
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