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secnidazole

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> Contraindications
> Special Precautions
> Adverse Drug Reactions
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> MIMS Class
> ATC Classification

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See related secnidazole information Abbreviation Index
Indications Listed in Dosage.
Dosage Adult: PO Invasive amoebiasis 1.5 g/day for 5 days. Amoebiasis; Giardiasis; Trichomoniasis Single dose of 2 g.
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Contraindications Hypersensitivity; pregnancy (1st trimester) and lactation.
Special Precautions Avoid alcohol and disulfiram. Avoid in patients with history of blood disorders.
Adverse Drug Reactions Nausea, gastralgia, change of taste, metallic taste, stomatitis, urticaria, rashes, leucopenia. Rarely vertigo, moderate neurological, digestive disturbances.
Drug Interactions Concurrent disulfiram admin may cause psychotic reactions. Disulfiram-like reactions with alcohol. Cimetidine may prolong half-life.
Potentially Fatal: Concurrent disulfiram admin may cause psychotic reactions. Disulfiram-like reactions with alcohol. Cimetidine may prolong half-life.
Mechanism of Action For details of the mechanism of action, pharmacology and pharmacokinetics and toxicology ... click to view secnidazole
MIMS Class Antiamoebics
ATC Classification P01AB07 - secnidazole ; Belongs to the class of nitroimidazole derivatives antiprotozoals. Used in the treatment amoebiasis and other protozoal diseases.
 
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Search related pubmed documents for secnidazole by indication/synonym:
Amoebiasis
Giardiasis
Trichomoniasis
Severe invasive amoebiasis




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