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Essential Prescribing Information

Duphaston® [tab]

Solvay Pharma [ Zuellig ]
MIMS Class : Oestrogens & Progesterones & Related Synthetic Drugs

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Contents
Dydrogesterone
Indications
Listed in Dosage.
Dosage
Dysfunctional uterine bleeding To arrest bleeding: 10 mg bid for 5-7 days. To prevent bleeding: 10 mg bid day 11-25 of the cycle. Threatened abortion 40 mg at once, then 10 mg every 8 hr until symptoms remit. Habitual abortion 10 mg bid until the 20th wk of pregnancy. Dysmenorrhea 10 mg bid from day 5-25 of the cycle. Endometriosis 10 mg bid or tid from day 5-25 of the cycle or continuously. Amenorrhea An estrogen once daily from day 1-25 of the cycle, together w/ 10 mg dydrogesterone bid from day 11-25 of the cycle. Premenstrual syndrome, irregular cycles 10 mg bid from day 11-25 of the cycle. Infertility due to luteal insufficiency 10 mg daily from day 14-25 of the cycle. Treatment should be maintained for at least 6 consecutive cycles. Postmenopausal complaints In combination w/ continuous estrogen therapy: 10-20 mg daily during the last 14 days/cycle of 28 days. In combination w/ cyclical estrogen therapy: 10 mg daily during the last 12-14 days of estrogen therapy.
Administration
May be taken with or without food
Special Precautions
Regular breast exams.
Adverse Drug Reactions
Breakthrough bleeding (prevented by increasing the dosage). Altered liver function w/ asthenia or malaise, jaundice & abdominal pain. Allergic rash, pruritus, urticaria.
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Storage
View Duphaston storage conditions for details to ensure optimal shelf-life.
Description
View Duphaston description for details of the chemical structure and excipients (inactive components).
Mechanism of Action
View Duphaston mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Oestrogens & Progesterones & Related Synthetic Drugs
ATC Classification
G03DB01 - Dydrogesterone ; Belongs to the class of pregnadien derivative progestogens used in progestogenic hormone preparations.
Poison Schedule
Rx
Presentation/Packing
FormPacking/PricePhoto
Duphaston tablet
Duphaston 10 mg x 20's (P928.92)

Manufacturer:Solvay Pharma
Distributor:Zuellig
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