Ferrous fumarate

Generic Medicine Info
Should be taken on an empty stomach. Best taken on an empty stomach. May be taken w/ meals to reduce GI discomfort.
Haemosiderosis, haemochromatosis; active peptic ulcer, inflammatory bowel disease (including regional enteritis, ulcerative colitis, intestinal strictures, diverticulae), haemoglobinopathies. Patient undergoing repeated blood transfusion. Concomitant use with dimercaprol, parenteral Fe.
Special Precautions
Patient with history of peptic ulcer; microcytic anaemia resistant to Fe monotherapy, rheumatoid arthritis. Post-gastrectomy patient. Not indicated for the treatment of anaemia resulting from causes other than Fe deficiency. Renal and hepatic impairment. Children. Avoid use in premature infants with low vitamin E stores, until replenished. Pregnancy and lactation. Monitoring Parameters Monitor Hb, haematocrit. May consider monitoring of RBC count, RBC indices, serum ferritin, transferrin saturation, total Fe-binding capacity, serum Fe concentration, erythrocyte protoporphyrin concentration.
Adverse Reactions
Significant: Dark stools. Gastrointestinal disorders: Nausea, vomiting, constipation, faecal impaction (particularly in elderly), gastrointestinal discomfort, diarrhoea, dental discolouration, heartburn. Immune system disorders: Allergic reactions. Metabolism and nutrition disorders: Anorexia. Renal and urinary disorders: Urinary discolouration.
Drug Interactions
May decrease the absorption of tetracyclines, Zn, penicillamine, fluoroquinolones (e.g. ciprofloxacin, norfloxacin, ofloxacin), levodopa, entacapone, bisphosphonates, levothyroxine, mycophenolic acid. Decreased absorption with Ca, Mg and other mineral supplements; bicarbonates, carbonates, Zn, trientine, tetracyclines, antacids, colestyramine. Concomitant use with chloramphenicol delays plasma clearance, incorporation into RBC, and interferes with erythropoiesis. May decrease the hypotensive effect of methyldopa. May reduce the absorption of vitamin E.
CIMS Class
Vitamins & Minerals (Pre & Post Natal) / Antianemics
ATC Classification
B03AA02 - ferrous fumarate ; Belongs to the class of oral iron bivalent preparations. Used in the treatment of anemia.
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