Significant: 1st dose orthostatic hypotension, syncope, floppy iris syndrome in cataract and glaucoma surgery, hypersensitivity reactions, MI exacerbations.
Cardiac disorders: Dyspnoea, palpitations.
Eye disorders: Visual impairment, blurred vision.
Gastrointestinal disorders: Constipation, vomiting, dry mouth, diarrhoea, nausea.
General disorders and administration site conditions: Malaise.
Nervous system disorders: Headache, dizziness.
Reproductive system and breast disorders: Ejaculation disorders including retrograde ejaculation, ejaculation failure, rarely, priapism.
Respiratory, thoracic and mediastinal disorders: Rhinitis.
Skin and subcutaneous tissue disorders: Pruritus, urticaria, skin desquamation including erythema multiforme, dermatitis exfoliative, rarely, Stevens-Johnson syndrome.
Vascular disorders: Hypotension, epistaxis.