NEW HIGHLIGHT
Ozempic

Ozempic

Manufacturer:

Novo Nordisk

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Semaglutide
Indications/Uses
Adjunct to diet & exercise in adults w/ insufficiently controlled type 2 DM as monotherapy when metformin is inappropriate due to intolerance or CIs; in addition to other medicinal products.
Dosage/Direction for Use
SC Initially 0.25 mg once wkly, increased to 0.5 mg once wkly after 4 wk. May be further increased to 1 mg once wkly after at least 4 wk to improve glycaemic control.
Administration
May be taken with or without food.
Contraindications
Special Precautions
Not to be administered IV/IM. Not as substitute for insulin. Discontinue use if pancreatitis is suspected. Not to be used in patients w/ type 1 DM or for diabetic ketoacidosis. Not recommended in patients w/ CHF NYHA class IV. Increased risk of hypoglycaemia in combination w/ insulin or sulfonylurea. GI effects; history of pancreatitis; diabetic retinopathy. Not recommended in end-stage renal disease. Severe renal & hepatic impairment. Women of childbearing potential must use effective contraception. Not to be used during pregnancy & lactation. Childn & adolescents <18 yr. Elderly ≥75 yr.
Adverse Reactions
Hypoglycaemia; nausea, diarrhoea. Decreased appetite; dizziness; diabetic retinopathy complications; vomiting, abdominal pain & distension, constipation, dyspepsia, gastritis, GERD, eructation, flatulence; cholelithiasis; fatigue; increased lipase & amylase, decreased wt.
Drug Interactions
Hypoglycaemia w/ insulin or sulfonylurea. Decreased AUC & Cmax of paracetamol. Frequent INR monitoring w/ warfarin. Drugs requiring rapid GI absorption.
MIMS Class
ATC Classification
A10BJ06 - semaglutide ; Belongs to the class of glucagon-like peptide-1 (GLP-1) analogues. Used in the treatment of diabetes.
Presentation/Packing
Form
Ozempic soln for inj 1.34 mg/mL
Packing/Price
1.5 mL x 1's;3 mL x 1's
/malaysia/image/info/ozempic soln for inj 1-34 mg-ml/1-34 mg-ml x 1-5 ml?id=1e169a88-b137-4152-832a-abe400f21f5f
/malaysia/image/info/ozempic soln for inj 1-34 mg-ml/1-34 mg-ml x 3 ml?id=f744e994-27d2-4895-b322-abe400f21f5f
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