Dolo-Neurobion

Dolo-Neurobion

Manufacturer:

P&G Phil

Distributor:

Zuellig
Concise Prescribing Info
Contents
Paracetamol 500 mg, vit B1 50 mg, vit B6 100 mg, vit B12 100 mcg
Indications/Uses
Mild to moderate pain including back pain (lumbalgia, radiculitis, spondylitis), neck pain, shoulder pain/shoulder-arm-syndrome (brachialgia), sciatica & carpal tunnel syndrome, pain after surgery & other painful conditions.
Dosage/Direction for Use
Adult, elderly, childn & adolescent >14 yr 1 tab once daily to tid. May be taken every 4-6 hr, until not exceeding 4,000 mg of paracetamol w/in 24 hr.
Administration
May be taken with or without food: May be taken w/ meals to reduce GI discomfort. Swallow whole w/ little liqd, do not chew.
Contraindications
Special Precautions
Patients w/ hepatic insufficiency, chronic alcohol abuse, severe renal insufficiency, impaired G6PD. Regular monitoring under long-term treatment. Rarely, paracetamol can cause serious, potentially fatal skin reactions, eg, AGEP, SJS, TEN.
Adverse Reactions
Vit B1, B6, B12: Hypersensitivity reactions, GI complaints, chromaturia. Paracetamol: Hypersensitivity reactions, skin reactions, GI disorders, hematological reactions, hepatic effects.
Drug Interactions
Reduced effect of L-dopa when in concomitant w/ vit B6. Decreased efficacy of vit B6 w/ pyridoxine antagonists eg, INH, cycloserine, penicillamine, hydralazine. Reduced blood level of vit B1 w/ loop diuretics eg, furosemide. Vit B12 deficiency w/ long-term use of acid lowering agents. Potentiated effect of oral anticoagulant (eg, warfarin). Risk of paracetamol toxicity w/ other potentially hepatotoxic drugs or drugs that induce liver microsomal enzymes (eg, antiepileptics). Decreased effectiveness of lamotrigine. Hepatotoxicity w/ alcohol.
ATC Classification
N02BE51 - paracetamol, combinations excl. psycholeptics ; Belongs to the class of anilide preparations. Used to relieve pain and fever.
Presentation/Packing
Form
Dolo-Neurobion FC tab
Packing/Price
100's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in