Adrenaline Aguettant

Adrenaline Aguettant

epinephrine

Manufacturer:

Laboratoire Aguettant

Distributor:

HK Medical Supplies

Marketer:

Aguettant
Concise Prescribing Info
Contents
Adrenaline
Indications/Uses
Cardiac arrest. Acute anaphylaxis in adults.
Dosage/Direction for Use
IV/intraosseous CPR Adult 1 mg (10 mL of 1:10,000 soln) every 3-5 min until return of spontaneous circulation. Only consider endotracheal use at 2-2.5 mg dose (20-25 mL of 1:10,000 soln) as a last resort if no other route of administration is accessible. Childn >5 kg 10 mcg/kg (0.1 mL/kg of 1:10,000 soln) every 3-5 min until return of spontaneous circulation. Max single dose: 1 mg (10 mL of 1:10,000 soln). Only consider endotracheal use at 100 mcg/kg dose (1 mL/kg of 1:10,000 soln) as a last resort if no other route of administration is accessible. Max single endotracheal dose: 2.5 mg (25 mL of 1:10,000 soln). Cardiac arrest following cardiac surgery 50 or 100 mcg IV (0.5 or 1 mL of 1:10,000 soln). IV bolus Acute anaphylaxis Adult 0.05 mg (0.5 mL of 1:10,000 soln) repeated as necessary until desired response is achieved.
Special Precautions
Indicated for emergency treatment; continuous medical supervision is necessary after administration. Patients w/ medical history of hyperthyroidism, hypercalcaemia, hypokalaemia, DM, cardiac disease or arterial HTN, brain damage or hardening of brain arteries, glaucoma, prostate disorders; on strict Na diet; w/ severe renal insufficiency. Pregnancy & lactation. Should not be used in neonates & infants weighing <5 kg. Elderly.
Adverse Reactions
Anxiety, dyspnoea, nervousness, fear, sweating, palpitations, tachycardia, pallor, tremors, weakness, dizziness, headache, nausea, vomiting, coldness of the extremities, hallucinations, syncopes, hyperglycaemia, hypokalaemia, metabolic acidosis, mydriasis. Necrosis at inj site following repeated local inj. In high doses or for patients sensitive to adrenaline: Cardiac dysrhythmia, HTN (w/ risk of cerebral haemorrhage), vasoconstriction, acute angina attacks, risk of acute MI.
Drug Interactions
Potential interaction w/ volatile halogen anaesth; certain antidepressants; drugs to treat high BP or heart conditions; drugs to treat diabetes.
MIMS Class
ATC Classification
C01CA24 - epinephrine ; Belongs to the class of adrenergic and dopaminergic cardiac stimulants excluding glycosides. Used in the treatment of hypotension.
Presentation/Packing
Form
Adrenaline Aguettant soln for inj 1 mg/10 mL
Packing/Price
10 mL x 10 × 1's
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