Very common (≥1/10), Common (≥1/100, <1/10), Uncommon (≥1/1000, <1/100), Rare (≥1/10000, <1/1000), Very rare (<1/10000 including isolated cases)
Musculoskeletal (bone, muscle or joint) pain which is sometimes severe.
Headache, dizziness, vertigo, abdominal pain, dyspepsia, constipation, diarrhoea, flatulence, oesophageal ulcer, dysphagia, abdominal distension, acid regurgitation, alopecia, pruritus, joint swelling, asthenia, peripheral oedema.
Dysgeusia, eye inflammation (uveitis, scleritis, episcleritis), nausea, vomiting, gastritis, oesophagitis, oesophageal erosions, melena, rash, erythema, transient symptoms as in an acute-phase response (myalgia, malaise and rarely, fever), typically in association with initiation of treatment.
Hypersensitivity reactions including urticaria and angioedema, symptomatic hypocalcaemia, often in association with predisposing conditions, oesophageal stricture, oropharyngeal ulceration, upper gastrointestinal PUBs (perforation, ulcers, bleeding), rash with photosensitivity, severe skin reactions including Stevens-Johnson syndrome and toxic epidermal necrolysis, osteonecrosis of the jaw; atypical subtrochanteric and diaphyseal femoral fractures (bisphosphonate class adverse reaction).