Commence treatment on the 1st day of the cycle. Women w/ amenorrhoea or very irregular menstrual bleeding can start immediately. Women should receive a progestogen-oestrogen containing prep. Hirsutism secondary to female androgenization
Initially 1 tab (50 mg) daily for 10 days mthly, may be reduced once a satisfactory response has been attained. Other severe signs of androgenization
2 tab daily from 1st to 10th day of the cycle. Postmenopausal or hysterectomised women
½-1 tab once daily for 21 days, followed by a 7-day tab-free interval. May be administered alone. Men Reduction of drive in sexual deviations
Initially 1 tab (50 mg) bd, if necessary may be increased to 2 tab bd-tds for a short period of time. When establishing maintenance dose or discontinuing the prep, reduce daily dose by 1 or ½ tab at intervals of several wk. To reduce initial increase of male sex hormones in treatment w/ LH-RH agonists
Initially 100 mg (2 tab) bd alone for 5-7 days, then 100 mg (2 tab) bd for 3-4 wk together w/ an LH-RH agonist. In long-term palliative treatment of advanced prostate cancer w/o orchiectomy
100 mg (2 tab) bd-tds. To treat hot flushes in patients under treatment w/ LH-RH analogues or who have had orchiectomy
50 mg (1 tab) once daily-tds, titrated to 100 mg (2 tab) tds if necessary.