Reduction of cholesterol & triglycerides in the blood when low fat diet, exercise & lifestyle changes have been unsuccessful in patients w/ hypercholesterolaemia or mixed hyperlipidaemia, heterozygous or homozygous familial hypercholesterolaemia.
Adult & childn ≥10 yr 10 mg once daily. Dose may be adjusted individually every ≤4 wk frequently. Max daily dose of 80 mg for adult & 20 mg once daily for childn. Hypercholesterolaemia or mixed hyperlipidaemia 20 mg/day. Heterozygous familial hypercholesterolaemia Initially 10 mg once daily. Adjust dose at 4-wk intervals up to 80 mg/day. Homozygous familial hypercholesterolaemia 80 mg daily.