Bricanyl

Bricanyl Adverse Reactions

terbutaline

Manufacturer:

AstraZeneca

Distributor:

Zuellig
/
Four Star
Full Prescribing Info
Adverse Reactions
Most of the side effects are characteristic of sympathomimetic amines. The incidence and severity of particular adverse reactions depend on the dose, route and rate of administration. An initial dose titration will often reduce adverse reactions. At recommended therapeutic doses, the frequency of adverse reactions is minimal.
Turbuhaler: Most of the reported adverse reactions are characteristic of sympathomimetic amines. The majority of these effects have reversed spontaneously within the 1st 1-2 weeks of treatment.
Urticaria and exanthema may occur.
In children sleep disturbances and behavioural disturbances been observed.
The frequency of adverse reactions is low at the recommended dose. Terbutaline given by inhalation is unlikely to produce significant systemic effects when given in recommended doses. Most of the adverse reactions are characteristic of sympathomimetic amines.
The majority of these effects have reversed spontaneously within the first 1-2 weeks of treatment. (See table.)

Click on icon to see table/diagram/image

Turbuhaler/Injection: More Common Reactions: Commonly observed side effects include tremor, headache, nervousness, increases in heart rate, tonic muscle cramps, hypokalaemia and palpitations.
Less Common Reactions: Cardiovascular: Ectopic beats.
Gastrointestinal: Nausea, vomiting, bad taste, diarrhoea.
General: Sweating.
Musculoskeletal: Muscle twitching, cramps.
Nervous System: Drowsiness, headache, dizziness, sleep disturbance, agitation, hyperactivity, restlessness.
Dermatological: Rash, urticaria, exanthema.
Severe or Life-Threatening Reactions: Cardiac arrhythmias (eg, atrial fibrillation, supraventricular tachycardia and extrasystoles) and myocardial ischaemia have been rarely reported.
Overdose of terbutaline preparations may produce significant tachycardia, arrhythmia and hypotension (see Overdosage).
In rare cases, through unknown mechanisms, drugs for inhalation may cause bronchospasm.
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