Four Star
Concise Prescribing Info
Hyoscine butylbromide
Tab GIT & GUT spasms. Symptomatic relief of Irritable Bowel Syndrome (IBS). Inj Acute spasm as in renal or biliary colic; radiology for differential diagnosis of obstruction; reduces spasm & pain in pyelography; diagnostic procedures where spasm may be a problem (eg, gastro-duodenal endoscopy).
Dosage/Direction for Use
Tab Adult & childn >12 yr 2 tab qds. IBS Initially 1 tab tds, may be increased if necessary. Childn 6-12 yr 1 tab tds. Inj Adult 1 amp (20 mg) IM or IV, repeated after ½ hr if necessary. Max: 100 mg/day.
May be taken with or without food: Tab: Swallow whole, do not break/crush/chew.
Hypersensitivity, myasthenia gravis, megacolon. Tab Glaucoma, confirmed bowel blockage, paralytic or obstructive ileus. Women of childbearing potential, pregnancy & lactation. Inj Narrow angle glaucoma, tachycardia, prostatic enlargement w/ urinary retention, mechanical stenoses of the GIT or paralytic ileus. Do not give by IM in patients on anticoagulants.
Special Precautions
Use w/ special care in patients w/ very fast heart rate or other heart problems (eg, cardiac failure, CHD, cardiac arrhythmia/HTN, cardiac surgery); fever. May affect ability to drive or operate machinery. Tab Take special care if patient has thyroid gland disorders (eg, overactive thyroid gland); difficult or painful urination (eg, men w/ prostate problems); constipation. Consult w/ the doctor or pharmacist in case of unexplained abdominal pain which persists or worsens or occurs w/ fever; feeling or being sick; changes or blood in bowel movements; abdominal tenderness; low BP; feeling faint. Contains sucrose. Childn <6 yr. Inj IOP elevations. Urinary retention. Women of childbearing potential, pregnancy & lactation.
Adverse Reactions
Tab Severe hypersensitivity (eg, difficulty breathing, feeling faint or dizzy). Allergic reactions eg, skin reactions (nettle rash, itching, rash, skin redness). Painful red eye w/ loss of vision. Inj Accommodation disorders; tachycardia; dizziness; dry mouth.
Drug Interactions
Intensified anticholinergic effect of TCAs or tetracyclic antidepressants; antihistamines; antiarrhythmics (eg, quinidine or dysopyramide); antipsychotics (eg, haloperidol or fluphenazine); anticholinergic bronchodilators (eg, tiotropium, ipratropium or atropine-like agents); amantadine. Concomitant use w/ dopamine antagonists (eg, metoclopramide) may reduce effects of both drugs in GIT. Inj Enhanced tachycardic effects of β-adrenergic agents.
MIMS Class
ATC Classification
A03BB01 - butylscopolamine ; Belongs to the class of belladonna alkaloids, semisynthetic, quaternary ammonium compounds. Used in the treatment of functional gastrointestinal disorders.
Tab: P1, Inj: P1S1S3
Buscopan inj 20 mg/mL
10 × 1's;100 × 1's
Buscopan sugar-coated tab 10 mg
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