Cetrimide


Generic Medicine Info
Indications and Dosage
Topical/Cutaneous
Antiseptic
Adult: As cetrimide 0.5% or 1% cream, or 1% or 2% lotion: Apply liberally to the affected area(s) as required. As cetrimide 0.5% spray solution: Spray to the affected area(s) 2-3 times daily.
Incompatibility
Incompatible with anionic surfactants, soaps, bentonite, iodine, phenylmercuric nitrate, alkali hydroxides.
Contraindications
Hypersensitivity.
Adverse Reactions
Significant: Hypersensitivity (prolonged and repeated use).
Skin and subcutaneous tissue disorders: Localised contact dermatitis; skin irritation, sensitisation, or dryness.
Patient Counseling Information
Avoid application on weeping or badly inflamed skin.
Action
Description: Cetrimide is a quaternary ammonium antiseptic with bactericidal action against gram positive and some gram negative (at higher concentrations) organisms, but ineffective against bacterial spore. It has variable antifungal activity and effective against some viruses.
Chemical Structure

Chemical Structure Image
Cetrimide

Source: National Center for Biotechnology Information. PubChem Database. Cetrimide, CID=14250, https://pubchem.ncbi.nlm.nih.gov/compound/Cetrimide (accessed on Jan. 21, 2020)

Storage
Store below 30°C. Protect from light, heat and moisture.
ATC Classification
D08AJ04 - cetrimide ; Belongs to the class of quaternary ammonium compound antiseptics. Used in the treatment of dermatological diseases.
D11AC01 - cetrimide ; Belongs to the class of medicated shampoos.
References
Anon. Cetrimide. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 05/05/2021.

Buckingham R (ed). Cetrimide. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 05/05/2021.

Cetavlex Cream (Derma UK Ltd). MHRA. https://products.mhra.gov.uk. Accessed 05/05/2021.

First Aid Antiseptic Spray or Boots Antiseptic Wound Wash (The Boots Company PLC). MHRA. https://products.mhra.gov.uk. Accessed 05/05/2021.

Vesagex Antiseptic Cream (Strides Pharma UK Ltd). MHRA. https://products.mhra.gov.uk. Accessed 05/05/2021.

Xortrim 1 1% w/v Lotion (Xorix Sdn Bhd). National Pharmaceutical Regulatory Agency - Ministry of Health Malaysia. https://www.npra.gov.my. Accessed 05/05/2021.

Xortrim 1,2; 1%, 2% w/v Lotion (Xorix Sdn. Bhd.). MIMS Malaysia. http://www.mims.com/malaysia. Accessed 20/05/2021.

Disclaimer: This information is independently developed by MIMS based on Cetrimide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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