Cidofovir - intravenous

Patient Medicine Information
Why do I need this medicine?
Cidofovir used together with probenecid (gout medicine) to treat infections caused by a virus called cytomegalovirus (CMV) especially in those patients with acquired immunodeficiency syndrome (AIDS).

This medicine may be used to treat other conditions as decided by your doctor.
How do I use this medicine?
Cidofovir injection is to be given intravenously (into the vein). It is delivered directly into the bloodstream via the blood vessel.

Your doctor or nurse will administer the injection for you.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Cidofovir.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
When should I not use this medicine?
Alert your doctor if you ever had an allergic reaction (breathlessness, rashes, swollen eyes) to probenecid or other sulfa-containing medications and similar antiviral medications.

Alert your doctor if you have kidney disease, as this medicine may not be suitable for you.

Do not use Cidofovir if you are pregnant or planning to have a baby soon. If you become pregnant while being treated with this medicine, alert your doctor immediately. Cidofovir may cause harm to your unborn child. You must use proven birth control methods while taking this medicine.

Do not use this medicine if you are breastfeeding.
What should I take note of while using this medicine?
For as long as you are using this medicine, you may need to have regular blood tests to check your body's response to the medicine and the health of your kidney. You may also need to have regular follow-up eye examinations. Your doctor will advise you how often you need to have them.
What side effects could I experience?
Cidofovir may cause any of the following side effects: headache, fever, nausea, vomiting, diarrhoea, weakness, back pain, depression, confusion and hallucinations.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:

- fever with persistent sore throat or mouth ulcers and unusual bleeding or bruising
- eye inflammation
- shortness of breath
- swollen ankles, feet or hands
- rashes accompanied with joint pain or stiffness, throat tightness and itching

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:

- antibiotics e.g. tobramycin, gentamicin
- medicines for HIV e.g. zidovudine, tenofovir
- medicines for fungal infections e.g. amphotericin B

This list does not include all medicines that may interact with Cidofovir.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Throw away remaining solution after 12 hours. Do not freeze.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on cidofovir - intravenous and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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