Film-coated tablet: Incompatibilities: Not applicable.
Infusion: Special precautions for disposal and other handling: The ciprofloxacin infusion solution is compatible with Ringer solution, Ringer lactate solution, 5 % and 10 % glucose solutions, and 5 % and 10 % fructose solutions. When ciprofloxacin infusion solutions are mixed with compatible infusion solutions, for microbial reasons and light sensitivity these solutions must be administered shortly after admixture.
As the infusion solution is sensitive to light, only remove the bottles from the folding box for use. In daylight the full efficacy of the solution is guaranteed over a period of 3 days.
For single use only.
At cool temperatures precipitation may occur, which will re-dissolve at room temperature (15 °C - 25 °C).
For ease of use the infusion vial stopper should be penetrated in the central ring. Penetration of the outer ring may result in damage to the vial stopper.
Any unused solution should be disposed off.
Incompatibilities: This medicinal product must not be mixed with other medicinal products except those mentioned previously in Special precautions for disposal and other handling.
Unless compatibility with other solutions/drugs has been confirmed, the infusion solution must always be administered separately. The visual signs of incompatibility are e.g. precipitation, clouding, and discoloration.
Incompatibility appears with all infusion solutions/drugs that are physically or chemically unstable at the pH of the solutions (e.g. penicillins, heparin solutions), especially in combination with solutions adjusted to an alkaline pH (pH of ciprofloxacin solutions: 3.9 - 4.5).