Pharmacotherapeutic Group: Long-Acting, Non-sedating Antihistamine/Decongestant.
Pharmacology: Loratadine is a potent long-acting tricyclic antihistamine with selective peripheral H1-receptor antagonistic activity.
Pseudoephedrine sulfate, one of the naturally occurring alkaloids of Ephedra and an orally administered vasoconstrictor, produces a gradual but sustained decongestant effect facilitating shrinkage of congested mucosa in upper respiratory areas.
The mucous membrane of the respiratory tract is decongested through the action on the sympathetic nerves.
The combination of loratadine and pseudoephedrine sulfate controls histamine-mediated symptoms and relieves nasal congestion associated with allergic rhinitis and the common cold.