Combivent Dosage/Direction for Use

ipratropium bromide + salbutamol


Boehringer Ingelheim


Agencia Lei Va Hong
Full Prescribing Info
Dosage/Direction for Use
Metered dose inhaler: Adults (including elderly patients): Two inhalations four times a day.
The dose may be increased as required up to a limit of 12 inhalations in 24 hours.
Patients should be advised to consult a doctor or the nearest hospital immediately in the case of acute or rapidly worsening dyspnoea (difficulty in breathing) if additional inhalations do not produce an adequate improvement.
Administration: The correct operation of the metered aerosol apparatus is essential for successful therapy.
Shake the aerosol canister and depress the valve two times before the apparatus is initially used.
Before each use the following rules should be observed: 1. Remove protective cap.
2. Shake the metered aerosol well before each use.
3. Breathe out deeply.
4. Hold the metered aerosol, and close lips over the mouthpiece. The arrow and the base of the container should be pointing upwards.
5. Breathe in as deeply as possible, pressing the base of the container firmly at the same time, this releases one metered dose. Hold the breath for a few seconds, then remove the mouthpiece from the mouth and breathe out.
The same action should be repeated for a second inhalation.
6. Replace the protective cap after use.
The container is under pressure and should on no account be opened by force or exposed to temperatures exceeding 50°C. As the container is not transparent it is not possible to see when the contents are used up, but shaking the container will show if there is any remaining fluid.
The mouthpiece should always be kept clean and can be washed with warm water. If soap or detergent is used, the mouthpiece should be thoroughly rinsed in clear water.
Unit dose vials: COMBIVENT inhalation solution in unit dose vials may be administered from a suitable nebuliser or an intermittent positive pressure ventilator.
The following dose is recommended for adults (including elderly patients) and adolescents over 12 years of age.
Treatment of acute attacks: 1 unit dose vial is sufficient for prompt symptom relief in many cases.
In severe cases, if an attack has not been relieved by one unit dose vial, two unit dose vials may be required. In these cases, patients should consult the doctor or the nearest hospital immediately.
Maintenance treatment: 1 unit dose vial three or four times daily.
Instructions for use: The unit dose vials are intended only for inhalation with suitable nebulising devices and should not be taken orally or administered parenterally.
1. Prepare the nebuliser for filling, according to the instructions provided by the manufacturer or doctor.
2. Tear one unit dose vial from the strip.
3. Open the unit dose vial by firmly twisting the top.
4. Squeeze the content of the unit dose vial into the nebuliser reservoir.
5. Assemble the nebuliser and use as directed.
6. After use throw away any solution left in the reservoir and clean the nebuliser, following the manufacturer's instructions.
Since the unit dose vials contain no preservative, it is important that the contents are used soon after opening and that a fresh vial is used for each administration to avoid microbial contamination. Partly used, opened or damaged unit dose vials should be discarded.
It is strongly recommended not to mix COMBIVENT solution for inhalation with other drugs in the same nebuliser.
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