CoPlavix Contraindications




DCH Auriga - Healthcare
Four Star
Full Prescribing Info
Due to the presence of both components of the medicinal product, CoPlavix is contraindicated in case of: Hypersensitivity to the active substances or to any of the excipients listed in Description; Severe hepatic impairment; Active pathological bleeding such as peptic ulcer or intracranial haemorrhage.
In addition, due to the presence of ASA, its use is also contraindicated in: Hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) and syndrome of asthma, rhinitis, and nasal polyps. Patients with pre-existing mastocytosis, in whom the use of acetylsalicylic acid may induce severe hypersensitivity reactions (including circulatory shock with flushing, hypotension, tachycardia and vomiting).
Severe renal impairment (creatinine clearance <30 ml/min).
Third trimester of pregnancy (see Use in Pregnancy & Lactation).
History of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy; active, or history of recurrent peptic ulcer/haemorrhage.
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