Dapsone Actavis

Dapsone Actavis

dapsone

Manufacturer:

Teva

Distributor:

Zuellig
Full Prescribing Info
Contents
Dapsone.
Description
Excipients/Inactive Ingredients: Lactose, magnesium stearate, maize starch, sodium lauryl sulphate.
Indications/Uses
Dapsone belongs to a group of medicines called antibacterials. It works by stopping the production of folic acid in certain bacteria, therefore stopping them growing.
Dapsone may be used for: leprosy; skin problems; prevention of malaria in combination with pyrimethamine; prevention of pneumonia in immunodeficient patients, especially in AIDS patients.
Dosage/Direction for Use
Always take Dapsone tablets exactly as the doctor has prescribed. If unsure, check with the doctor or pharmacist.
Swallow the tablets with some water.
The usual doses are: Adults and children over 12 years: Multibacillary leprosy: 100 mg for at least two years.
Paucibacillary leprosy: 100 mg daily for at least six months.
Malaria prophylaxis: 100 mg weekly with 12.5 mg pyrimethamine.
Dermatitis herpetiformis: Initially 50 mg daily which may be gradually increased to 300 mg daily and then reduced to a usual maintenance dose of 25 mg-50 mg daily.
Pneumocystis carinii pneumonia: In combination with trimethoprim, 50-100 mg daily or 100 mg twice weekly or 200 mg once weekly.
Elderly: In case of damaged liver the doctor may give a lower dose.
Children 6-12 years: Multibacillary leprosy: 50 mg for at least two years.
Paucibacillary leprosy: 50 mg for at least six months.
Continue to take them for as long as the doctor has prescribed, it may be dangerous to stop without their advice.
In case of missed dose: If the patient forgets to take the tablets: Do not take a double dose to make up for a forgotten dose. If the patient forgets to take a dose take it as soon as remembered it and then take the next dose at the right time.
Overdosage
If the patient takes more than the prescribed: If the patient (or someone else) swallows a lot of tablets at the same time, or a child may have swallowed any, contact the nearest hospital casualty department or tell the doctor immediately.
Contraindications
Do not take Dapsone tablets and tell the doctor if the patient: is allergic (hypersensitive) to dapsone, any of the other ingredients in the tablet, or to similar medicines such as sulphonamide or sulphone (see Description). An allergic reaction may include a rash, itching, difficulty breathing or swelling of the face, lips throat or tongue; suffers from severe anemia; has porphyria (a genetic or inherited disorder of the red blood pigment, haemoglobin); suffers from severe glucose-6-phosphate dehydrogenase deficiency (G6PD), this can cause episodes of anaemia after eating certain foods such as fava beans (favism).
Special Precautions
Take special care with Dapsone tablets and tell the doctor if the patient: suffers from other blood disorders; suffers from heart or lung disease.
Sugar intolerance: If told to have an intolerance to some sugars, contact the doctor before taking this medicine, as it contains lactose.
Use In Pregnancy & Lactation
If the patient is pregnant or planning to become pregnant, the doctor may prescribe folic acid supplements.
Dapsone can be present in breast milk. There has been a report of anaemia in an infant being breast fed by a mother taking Dapsone tablets.
If the patient is concerned, check with the doctor or pharmacist.
Ask the doctor or pharmacist for advice before taking taking any medicines.
Side Effects
Like all medicines, Dapsone tablets can cause side effects, particularly when the patient first starts taking it, although not everybody gets them. Please tell the doctor or pharmacist in case of any of the following effects or any effects not listed.
Contact the doctor at once if the following occur: Dapsone syndrome: a 'dapsone syndrome' may occur after 3-6 weeks of treatment. Symptoms always include rash, fever and changes in blood cells. It is important to seek medical help immediately as severe skin reactions, inflammation of the liver, kidney damage and mental illness have occurred if treatment is not stopped or reduced. Some deaths have been reported.
Effects on leprosy: if the patient is being treated for leprosy and the condition does not improve or gets eye or nerve damage, talk to the doctor.
Tell the doctor if the patient notices any of the following side effects or notices any other effects not listed: Effects on the blood: anaemia caused by destruction of red blood cells, changes in the type and number of other blood cells (the patient may develop ulcers in the mouth or on the skin).
Effects on the skin: rash which can be raised, discoloured, tender, destructive or itchy, sensitivity to sunlight or artificial light such as sun-bed (symptoms such as tingling, burning or redness of the skin). Rarely skin conditions may be associated with fever, malaise, lung or kidney damage.
Effects on the nervous system: headache, difficulty sleeping, nerve damage which may cause tingling in the arms or legs and some weakness.
Effects on the gastrointestinal system: loss of appetite, feeling or being sick, inflammation of the liver.
Other effects: fast heart beat, mental disturbances, changes in liver function tests, jaundice.
Drug Interactions
Please tell the doctor or pharmacist if the patient is taking or has recently taken any other medicines, including medicines obtained without a prescription. Especially: probenecid (to treat gout); rifampicin or trimethoprim (antibiotics to treat infections).
Ask the doctor or pharmacist for advice before taking any medicines.
Caution For Usage
Medicines should not be disposed of via wastewater or household waste. Ask the pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
Storage
Store below 25°C in a dry place.
MIMS Class
ATC Classification
J04BA02 - dapsone ; Belongs to the class of drugs used in the systemic treatment of lepra.
Presentation/Packing
Tab 100 mg (circular, white uncoated) x 28's.
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $768 a year.
Sign up for free
Already a member? Sign in