Dexamet Solution for Inj

Dexamet Solution for Inj



Daewon Pharm


Star Medical Supplies
Cordial Trading
Full Prescribing Info
Dexamethasone sodium phosphate.
Each mL contains 5 mg Dexamethasone Sodium Phosphate.
For general and local glucocorticoid injection therapy and acute condition in which intravenous glucocorticoids may be life-saving.
Dosage/Direction for Use
By intramuscular injection or slow intravenous injection or infusion.
Adult: Initially 0.5-24 mg.
Child: 200-400 micrograms/kg daily.
For acute life-threatening situations (e.g. anaphylaxis, acute severe asthma) substantially higher dosages may be needed. Cerebral oedema (adults): initial dose 8-16 mg IV followed by 5 mg IV or IM every 6 hours, until a satisfactory result has been obtained. In brain surgery these dosages may be necessary until several days after the operation.
Thereafter, the dosage has to be tapered off gradually.
Increase of intracranial pressure associated with brain tumours can be counteracted by continuous treatment.
For local treatment, the following dosages can be recommended: Intra-articulary: 1.6-3 mg large joints; 0.6-0.8 mg small joints.
Intrabusally: 1.6-3 mg.
Tendon sheaths: 0.3-0.8 mg.
The frequency of these injections may vary from once every 3-5 days to once every 2-3 weeks. For rectal drip in cases of ulcerative colitis: 4 mg diluted in 120 mL saline.
Systemic infection unless specific anti-infective therapy is employed.
Hypersensitivity to any ingredient.
Local injection of glucocorticoid is contraindicated in bacteraemia and systemic fungal infections, unstable joints, infection of the injection site.
Special Precautions
Before taking Dexamet Solution for Inj, tell the doctor if the patient: Has cancer of the blood; kidney or liver problems; high blood pressure or heart disease; diabetes or family history of diabetes; muscle weakness with this or other steroids before; osteporosis; glaucoma; peptic ulcer; mental problems or mental illness; epilepsy; migraines; infection with parasites; tuberculosis; stunted growth; Cushing's syndrome; head injury; stroke.
If not sure, talk to the doctor.
Serious Neurologic Adverse Reactions with Epidural Administration: Serious neurologic events, some resulting in death, have been reported with epidural injection of corticosteroids. Specific events reported include, but are not limited to, spinal cord infarction, paraplegia, quadriplegia cortical blindness, and stroke. These serious neurologic events have been reported with and without use of fluoroscopy. The safety and effectiveness of epidural administration of corticosteroids have not been established, and corticosteroids are not approved for this use.
If a child is having Dexamet Solution for Inj, it is important that the doctor monitors their growth and development regularly.
Dexamet Solution for Inj should not be routinely given to premature babies with respiratory problems.
If the patient develops an infection while having Dexamet Solution for Inj, please inform the doctor.
If the patient is having Dexamet Solution for Inj, avoid contact with anyone who has chicken pox, shingles or measles.
Driving and using machines: Dexamet Solution for Inj does not likely affect the ability to drive or use any tools or machines.
Use In Pregnancy & Lactation
Talk to the doctor before having Dexamet Solution for Inj if the patient is pregnant, planning to become pregnant or breast-feeding.
Side Effects
Like all medicines, Dexamet Solution for Inj may cause following side effects: Stomach and gut problem such as diarrhea, feeling or being sick; inflamed pancreas such as severe pain in the back or tummy; problem with salts in the blood; heart and blood problem such as high blood pressure, blood clots; bone problems such as osteoporosis, risk of fractures, bone disease, damaged tendons and joint; recurring infections such as children pox; skin problem; eye problem such as glaucoma, cataracts, eye infections; hormone problems such as Cushingoid or moon face; nervous system problem such as headache.
If any of these side effects is noted, please tell the doctor.
Serious side effects: tell a doctor straight away.
Steroids including Dexamethasone can cause serious mental health problems. These include: Feeling depressed, including thinking about suicide; feeling high (mania) or moods that go up and down; feeling anxious, having problems sleeping, difficulty in thinking or being confused and losing memory; feeling, seeing or hearing things that do not exist; having strange and frightening thoughts, changes in action or having feelings of being alone.
If the patient has an allergic reaction to Dexamethasone see a doctor straight away.
An allergic reaction may include: Any kind of skin rash or itching of the skin; difficulty in breathing or collapse.
Drug Interactions
Tell the doctor if the patient is taking other medicines as follows: High blood pressure medicine or diuretics; antibiotics; medicine to treat epilepsy; medicine to control pain or lower inflammation; diabetes medicines; lower potassium level medicine; treat myasthenia medicine; anti-cancer treatment; ephedrine; acetazolamide; carbenoxolone.
Store at temperature not exceeding 30°C.
ATC Classification
H02AB02 - dexamethasone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Soln for inj (amp) 5 mg/mL x 10's.
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $768 a year.
Sign up for free
Already a member? Sign in