SC Atopic dermatitis Adult Initially 600 mg (two 300-mg inj consecutively administered at different inj site), followed by 300 mg every other wk.
Adolescent 12-17 yr, weighing ≥60 kg Initially 600 mg, followed by 300 mg every other wk,
<60 kg Initially 400 mg (two 200-mg inj consecutively administered at different inj site), followed by 200 mg every other wk.
Childn 6-11 yr, weighing ≥60 kg Initially 600 mg, followed by 300 mg every other wk,
15 to <60 kg Initially 300 mg on day 1, followed by 300 mg on day 15. Subsequent doses: 300 mg every 4 wk, starting 4 wk after day 15 dose. Dose may be increased to 200 mg every other wk based on physician's assessment.
Asthma Adult & adolescent ≥12 yr Initially 400 mg, followed by 200 mg every other wk.
Patient w/ severe asthma & who are on oral corticosteroids; patient w/ severe asthma & co-morbid moderate to severe atopic dermatitis; adult w/ co-morbid severe chronic rhinosinusitis w/ nasal polyposis Initially 600 mg, followed by 300 mg every other wk.
CRSwNP Adult Initially 300 mg, followed by 300 mg every other wk.
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