Topical corticosteroids should not be extensively in large amounts or for protracted period in pregnant patients or patients who are planning to become pregnant. Adequate and well-controlled studies in humans have not been done. Studies in animals have shown that topical corticosteroids are systematically absorbed and may cause fetal abnormalities, especially when used in large amounts, with occlusive dressings, for prolonged period of time, or if the more potent agents are used.
It is not known whether topical corticosteroids are distributed into breast milk. However, problems in humans have not been documented. Systemic corticosteroids are distributed into breast milk and may cause unwanted effects, such as growth suppression, in the infant. Topical corticosteroids should not be applied to the breasts prior to nursing.