lidocaine + prilocaine


Kolmar Korea


Yu Chun
SB Pharma
Full Prescribing Info
Lidocaine, prilocaine.
Each gram contains Lidocaine (lignocaine) 25 mg, Prilocaine 25 mg, Methylparaben 1.6 mg, Propylparaben 0.4 mg.
Adults: Topical anaesthesia of the skin in connection with: intact skin prior to minor dermatological procedures (e.g. needle insertion and surgical treatment of localised lesions) and prior to dermal procedures on larger areas e.g. split skin grafting.
Dermal procedures on newly shaven skin of large body areas e.g. laser hair removal.
Topical anaesthesia of the genital mucosa, e.g. prior to superficial surgical procedures or prior to infiltration anaesthesia of mucosa.
Topical anaesthesia of leg ulcers to facilitate mechanical cleansing/debridement.
Paediatric: ENCAIN Cream is indicated in the following age groups: neonates 0-2 months, infants 3-11 months and children 1-11 years, for topical anaesthesia of the skin in connection with needle insertion e.g. iv catheters or blood sampling and in superficial surgical procedure. ENCAIN Cream is also indicated in children with atopic dermatitis prior to curettage of mollusca.
Studies have failed to demonstrate efficacy of ENCAIN Cream for heel lancing in newborn infants.
Dosage/Direction for Use

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One gram of ENCAIN cream pressed out of a tube of 30g is approximately 3.5 cm.
Persons frequently applying or removing cream should ensure that contact is avoided in order to prevent the development of hypersensitivity.
Paediatric population: Adolescents ≥ 12 years: As for adults (approximately 2 g ENCAIN applied under an occlusive dressing for a minimum of 60 minutes, maximum 5 hours).
Term newborn infants, infants and children ≤ 11 years: In term newborn infants and infants < 3 months, only one single dose should be applied in any 24 hour period.
For children aged 3 months and above, a maximum of 2 doses, separated by at least 12 hours can be given within any 24 hour period. If, based on clinical need, a decision is nevertheless taken to use two applications in children under the age of 3 months.
The safety of ENCAIN in pre-term newborn infants has not been established. Use of ENCAIN is not recommended in pre-term infants.
Use of ENCAIN is not recommended in infants less than 3 months of age receiving treatment with methaemoglobin-inducing drugs.
For all age groups analgesic efficacy may decline if the skin application time is more than 5 hours. Procedures on intact skin should begin soon after the occlusive dressing is removed.
On the genital mucosa analgesic efficacy declines after 10-15 minutes and therefore the procedure should be commenced immediately.
Methods of dose estimation: ENCAIN is available in 5 g and 30 g tubes. To dispense 1 g of ENCAIN from either tube size, apply the cream to a circular area with a diameter of approx. 18 mm (a 1 pence coin) and depth of approx. 4 to 5 mm.
If high levels of accuracy in dosing are required to prevent overdose (i.e. at doses approaching the maximum in neonates or if two applications may be required in a 24 h period), a syringe can be used where 1 ml = 1 g.
A string of cream can be used to define the quantity of ENCAIN administered from the 30 g tube where 1 g = 3.5 cm; however, a string of cream may not be appropri­ate for all application needs, e.g. when administering a low dose to small surface areas.
Store below 25°C.
ATC Classification
N01BB20 - combinations ; Belongs to the class of amides. Used as local anesthetics.
Cream 10 g, 500 g.
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