HIGHLIGHT
Enhertu

Enhertu Drug Interactions

Manufacturer:

Daiichi Sankyo

Distributor:

Zuellig

Marketer:

Daiichi Sankyo
/
AstraZeneca
The information highlighted (if any) are the most recent updates for this brand.
Full Prescribing Info
Drug Interactions
Co-administration with ritonavir, an inhibitor of OATP1B, CYP3A and P-gp, or with itraconazole, a strong inhibitor of CYP3A and P-gp, resulted in no clinically meaningful (approximately 10-20%) increase in exposures of trastuzumab deruxtecan or the released topoisomerase I inhibitor, DXd. No dose adjustment is required during co-administration of trastuzumab deruxtecan with medicinal products that are inhibitors of CYP3A or OATP1B or P-gp transporters (see Pharmacology: Pharmacokinetics under Actions).
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