Entocort Dosage/Direction for Use





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Dosage/Direction for Use
Adults: The dose should be adjusted depending on the activity of the disease. The recommended dose in active Crohn's disease is 9 mg (3 capsules) daily for 8 weeks. The recommended dose in remission is 6 mg (2 capsules). The dose should be kept at the minimum required. Full effect is usually achieved within 2-4 weeks. The capsules should be taken in the morning.
The capsule should be swallowed whole, and must not be divided or chewed.
To replace prednisolone in steroid dependent patients, the recommended dose is 6 mg once daily. When treatment with Entocort capsules is initiated the prednisolone dose should be tapered.
Elderly: Dosage as for adults. Experience of treatment with Entocort capsules in elderly patients is limited.
Children: At present there is no experience of treatment with Entocort capsules in children.
Patients with liver disease: Impaired liver function increases the systemic bioavailability of budesonide.
The dose may need to be increased or additional systemic glucocorticoid treatment given in stress situations, fever and strain.
Diabetics may require higher insulin doses during glucocorticoid therapy.
Treatment with Entocort capsules should be tapered before cessation (see Precautions).
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