Menopausal hormone replacement therapy
Adult: 0.5-3 mg daily for 1 mth followed by 0.5-1 mg daily; or 0.25-2 mg daily in combination with other natural oestrogens. A progestogen is required if administered to women with a uterus.
Infertility due to cervical hostility
Adult: 0.25-1 mg/day on days 6-15 of the menstrual cycle. Increase dose each mth until an optimal effect is obtained.
Menopausal atrophic vaginitis
Adult: As 0.01% or 0.1% cream or 500 mcg pessary: Apply 500 mcg once daily, reduce to twice wkly subsequently.