Etoxib Special Precautions





Hind Wing
Four Star
Full Prescribing Info
Special Precautions
Talk to the doctor or pharmacist before taking Etoxib if: A history of stomach bleeding or ulcers is present.
Dehydrated, for example by a prolonged bout of vomiting or diarrhoea.
Swelling due to fluid retention is present.
A history of heart failure, or any other form of heart disease, is present.
A history of high blood pressure is present. Etoxib can increase blood pressure in some people, especially in high doses, and the doctor will want to check the blood pressure from time to time.
Any history of liver or kidney disease is present.
Being treated for an infection. Etoxib can mask or hide a fever, which is a sign of infection.
Diabetes, high cholesterol is present, or a smoker. These can increase the risk of heart disease.
A woman trying to become pregnant.
Over 65 years of age.
If not sure if any of the previously mentioned applies, talk to the doctor before taking Etoxib to see if this medicine is suitable.
Etoxib increases risk of cardiovascular adverse effects.
Etoxib works equally well in older and younger adult patients.
In rare cases, Etoxib has been associated with severe liver injury.
Cardiovascular Risk: NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use. Patients with cardiovascular disease or risk factors for cardiovascular disease may be at greater risk.
Gastrointestinal Risk: NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal events.
Renal Effects: Long-term administration of NSAIDs has resulted in renal papillary necrosis and other renal injury. Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. In these patients, administration of a NSAID may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation. Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. Discontinuation of NSAID therapy is usually followed by recovery to the pretreatment state.
Advanced Renal Disease: No information is available from controlled clinical studies regarding the use of Etoxib in patients with advanced renal disease. Therefore, treatment with Etoxib is not recommended in these patients with advanced renal disease. If therapy must be initiated, close monitoring of the patient's renal function is advisable.
Driving and using machines: Dizziness and sleepiness have been reported in some patients taking Etoxib.
Do not drive if experiencing dizziness or sleepiness.
Do not use any tools or machines if experiencing dizziness or sleepiness.
Use in Elderly: If over 65 years of age, the doctor will want to appropriately keep a check. No dosage adjustment is necessary for patients over 65 years of age.
Use in Children: Do not give this medicine to children and adolescents under 16 years of age.
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