Hypersensitivity to the active substances, to dihydropyridine derivatives, or to any of the excipients listed in Description.
Severe hepatic impairment, biliary cirrhosis or cholestasis.
Concomitant use of Exforge with aliskiren-containing products in patients with diabetes mellitus or renal impairment (GFR <60 ml/min/1.73 m2) (see Precautions, Interactions and Pharmacology: Pharmacodynamics under Actions).
Second and third trimesters of pregnancy (see sections Precautions and Use in Pregnancy & Lactation).
Shock (including cardiogenic shock).
Obstruction of the outflow tract of the left ventricle (e.g. hypertrophic obstructive cardiomyopathy and high grade aortic stenosis).
Haemodynamically unstable heart failure after acute myocardial infarction.