When co-administered w/ a statin, perform liver function tests at initiation of therapy. Increased risk of rhabdomyolysis & myopathy. Discontinue therapy if cholelithiasis is suspected. Monitor concentrations of ciclosporin prior to therapy. Monitor INR if co-administered w/ warfarin & other coumarin anticoagulant or fluindione. Rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Moderate or severe hepatic impairment. May impair ability to drive or operate machinery. Pregnancy & lactation. Childn (10-17 yr).