Fasturtec also contains the following excipients: Powder: Alanine, mannitol, disodium phosphate dodecahydrate, disodium diphosphate dihydrate and sodium dihydrogen phosphate dihydrate. Solvent: Poloxamer 188 and Water for Injections.
Fasturtec is a recombinant urate-oxidase enzyme produced by genetically modified Saccharomyces cerevisiae strain. Rasburicase is a tetrameric protein with identical subunits of a molecular mass of about 34 kDa.
*One enzymatic activity (EAU) corresponds to the enzyme activity that converts 1 micromol of uric acid into allantoin per minute under the operating conditions described: +30°C ±1°C TEA pH 8.9 buffer.