Incorrect administration may cause leakage at inj site & lead to skin irritation & potentially long-lasting brown discolouration at inj site; immediately stop administration when this occurs. Patients w/ history of medicine allergy; SLE; RA; severe asthma, eczema or other allergies; infection; liver disorders. Patients on Na-controlled diet. Pregnancy & lactation. Should not be given to childn <14 yr.