Muscle weakness, steroid myopathy, loss of muscle mass, osteoporosis, vertebral compression fractures, aseptic necrosis of femoral & humeral heads, pathologic fracture of long bones & spontaneous fractures. Peptic ulcer, pancreatitis, abdominal distension, ulcerative oesophagitis. Impaired wound healing, thin fragile skin, bruising, petechiae & ecchymoses, facial erythema, increased sweating, subcutaneous fat atrophy, purpura, striae, hyperpigmentation, hirsutism & acneiform eruptions, suppression of reactions to skin tests. Convulsion, papilloedema, vertigo, headache, mental disturbances. Endocrine abnormalities, hyperglycemia, negative nitrogen balance. Necrotising angitis, thrombophlebitis, aggravation or masking of infections, insomnia, syncopal episodes & anaphylactoid reactions.