Chronic lymphocytic leukemia (CLL) of B-cell type w/ sufficient bone marrow function. 1st- or 2nd-line treatment of sufficient bone marrow function. 1st-line treatment in later stages (RaI III/IV, Binet C) or in earlier stages if disease-related symptoms make treatment desirable.
Monitor signs of neurological side effects, haematological & non-haematological toxicity or autoimmune haemolytic anaemia. Renal & hepatic impairment. AML patients. Discontinue in case of haemolysis. Childn.