In rare cases, pruritus, burning or redness can be observed. However, these adverse reactions can also be associated with the symptoms of the vaginal infection. In these cases it is not necessary to stop the treatment.
Bleeding surface defects (erosions) in the vagina were reported in individual cases. In these cases, the vaginal surface (vaginal epithelium) was predamaged eg, in consequence of oestrogen deficiency or distinct inflammation.
Some very rare cases of fever have been reported. In these cases, the treatment should be stopped and inform the physician.