Each tablet contains Folic acid 5 mg.
It is indicated for the treatment of megaloblastic anaemia caused by deficiency of folic acid. It is also indicated in pregnancy to supply a maintenance dosage of folic acid.
In the treatment of megaloblastic anaemia, folic acid may be given in an initial dosage of 10 to 20 mg daily for 14 days, or until a haemopoietic response is obtained. The daily maintenance dose is 2.5 to 10 mg.
Children may be given 5 to 15 mg daily according to the severity of the deficiency state.
For maintenance dosage in pregnancy, folic acid may be given in dosage of 5 mg daily during first trimester of pregnancy.
The possibility of serious toxic effects due to overdosage appears remote.
Treatment: An emetic should be administered as soon as possible following by gastric lavage if possible.
It is contraindicated in patients who are sensitive to it.
Folic acid should never be given alone or in conjunction with inadequate amounts of hydroxocobalamin for the treatment of megaloblastic or pernicious anaemia. Though folic acid produces a haemopoietic response, it fails to prevent the onset of subacute combined degeneration of the cord. Folic acid should not be given before a diagnosis has been fully established. Large and continuous doses of folic acid may lower the blood concentration of vitamin B12. The availability of folates may be inhibited by gastric acidity and the presence of ascorbate in the gastrointestinal tract.
Metformin reduces intestinal absorption of folic acid and phenytoin may cause folate depletion. Folic acid does not correct folate deficiency due to dihydrofolate reductase inhibitors.
Folic acid is usually well tolerated. However, allergic sensitization has been reported following oral administration.
Store below 30°C.
Shelf-Life: 5 years.
B03BB01 - folic acid ; Belongs to the class of folic acid and derivatives. Used in the treatment of anemia.
Tab 5 mg (Round, pale yellow, standard convex, plain with score on one side) x 1000's.