Galvus保胰健

Galvus

vildagliptin

Manufacturer:

Novartis

Distributor:

Zuellig
/
Four Star
Concise Prescribing Info
Contents
Vildagliptin
Indications/Uses
Type 2 DM as monotherapy or in dual combination w/ metformin, a sulphonylurea or a thiazolidinedione in patients w/ insufficient glycaemic control; or in triple combination w/ a sulphonylurea & metformin when diet & exercise + dual therapy w/ these agents do not provide adequate glycaemic control; or in combination w/ insulin (w/ or w/o metformin) when diet & exercise & a stable dose of insulin do not provide adequate glycaemic control.
Dosage/Direction for Use
Monotherapy or combination therapy w/ metformin, thiazolidinedione, metformin + sulphonylurea, insulin 100 mg in 2 divided doses in the morning & evening. Combination therapy w/ sulphonylurea 50 mg once daily in the morning.
Administration
May be taken with or without food.
Contraindications
Special Precautions
Should not be used in type 1 diabetes or diabetic ketoacidosis. End-stage renal disease on haemodialysis, renal impairment. Hepatic impairment. Perform liver function test prior to & during treatment at 3-mth intervals during the 1st yr & periodically thereafter. Discontinue use if AST/ALT ≥3 x ULN persists, or if jaundice & pancreatitis develop. Cardiac failure (NYHA class III-IV). Monitor for skin disorders eg, blistering & ulceration. Risk of developing acute pancreatitis; hypoglycaemia. Rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Pregnancy & lactation.
Adverse Reactions
Hypoglycaemia; tremor, headache, dizziness; nausea; asthenia; increased wt; peripheral oedema; hyperhidrosis; chills, GERD.
Drug Interactions
Hypoglycaemic effect may be reduced w/ thiazides, corticosteroids, thyroid prep, sympathomimetics.
MIMS Class
Antidiabetic Agents
ATC Classification
A10BH02 - vildagliptin ; Belongs to the class of dipeptidyl peptidase 4 (DPP-4) inhibitors. Used in the treatment of diabetes.
Presentation/Packing
Form
Galvus tab 50 mg
Packing/Price
28's;56's
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