Glimel

Glimel

glibenclamide

Manufacturer:

Alphapharm

Distributor:

Luen Cheong Hong
Concise Prescribing Info
Contents
Glibenclamide
Indications/Uses
Maturity onset diabetes when dietary control alone proves inadequate & diabetes is considered suitable for oral therapy.
Dosage/Direction for Use
Initially 2.5 mg daily. May increase dose in steps of 2.5 mg at intervals of 7 days, max: 15 mg.
Administration
Should be taken with food.
Contraindications
Juvenile DM, serious metabolic decompensation w/ acidosis, in particular precoma & coma. Serious renal impairment especially if due to glomerular lesions. Adrenocortical insufficiency, in circumstances of unusual stress.
Special Precautions
Pregnancy, lactation. Childn.
Adverse Reactions
GI symptoms (seldom). Allergic skin reactions, hypoglycaemic reactions. Haematopoietic reactions.
Drug Interactions
Actions may be enhanced by sulfonamides, phenylbutazone, salicylates, chloramphenicol, coumarin derivatives, ethionamide, tetracycline compds, cyclophosphamide, MAOIs, β-blockers, bezafibrate, clofibrate, fenfluramine, probenecid. Actions may be reduced by long-term therapy w/ corticosteroids & thiazide diuretics, adrenaline, OC, phenothiazine derivatives, thyroid hormones, nicotinic acid & laxative abuse.
MIMS Class
ATC Classification
A10BB01 - glibenclamide ; Belongs to the class of sulfonylureas. Used in the treatment of diabetes.
Presentation/Packing
Form
Glimel tab 5 mg
Packing/Price
1000's ($200.00/pack)
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