Instructions for dilution: For single use only. Any unused portion should be discarded.
The diluted injections and infusions are to be inspected visually for particulate matter prior to administration. They should only be used if the solution is clear and free from particles.
Adults: The contents of a 1 ml ampoule can be diluted to a volume of 5 ml; the contents of a 3 ml ampoule can be diluted to a volume of 15 ml.
Granisetron Kabi can also be diluted in 20 to 50 ml compatible infusion fluid and then given over five minutes as an intravenous infusion.
Granisetron Kabi can only be diluted with the following solutions: 0.9 % w/v sodium chloride injection, 5 % w/v glucose injection, Lactated Ringer's Solution; No other diluents should be used.
Children 2 years of age and older: To prepare the dose of 10 - 40 μg/kg, the appropriate volume is withdrawn and diluted with infusion fluid (as for adults) to a total volume of 10 to 30 ml.
As a general precaution, Granisetron Kabi should not be mixed in solution with other drugs.