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Harnal OCAS奧利新

Harnal OCAS

tamsulosin

Manufacturer:

Astellas

Distributor:

Firma Chun Cheong
/
DKSH
Concise Prescribing Info
Contents
Tamsulosin HCl
Indications/Uses
Lower urinary tract symptoms (LUTS) associated w/ benign prostatic hyperplasia (BPH).
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Dosage/Direction for Use
1 tab daily.
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Overdosage
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Administration
May be taken with or without food: Swallow whole, do not open/chew/crush.
Contraindications
Hypersensitivity, including drug-induced angioedema.
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Special Precautions
Orthostatic hypotension can occur during treatment. Perform digital rectal exam & determine prostate specific antigen (PSA) before treatment & at regular intervals thereafter. Risk of intraoperative floppy iris syndrome (IFIS) during cataract & glaucoma surgery. Not recommended to initiate therapy in patients w/ scheduled cataract or glaucoma surgery. Should not be given in combination w/ strong CYP3A4 inhibitors in patients w/ poor metaboliser CYP2D6 phenotype. Use w/ caution in combination w/ strong & moderate CYP3A4 inhibitors. Patients w/ history of orthostatic hypotension; sulfonamide allergy. May impair ability to drive or operate machinery. Patients w/ severe renal impairment (CrCl <10 mL/min); severe hepatic dysfunction. For male patients only. No relevant indication in childn.
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Adverse Reactions
Dizziness; ejaculation disorders including retrograde ejaculation & ejaculation failure.
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Drug Interactions
Increased plasma levels w/ cimetidine. Decreased plasma levels w/ furosemide. Increased elimination rate w/ diclofenac & warfarin. Increased AUC & Cmax w/ ketoconazole (strong CYP3A4 inhibitor); paroxetine (strong CYP2D6 inhibitor). Hypotensive effects w/ other α1-adrenoceptor antagonists.
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Caution For Usage
For caution against possible variation of physical aspect of medicine... Click to view Harnal OCAS detailed prescribing information
Storage
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Description
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Action
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MIMS Class
Drugs for Bladder & Prostate Disorders
ATC Classification
G04CA02 - tamsulosin ; Belongs to the class of alpha-adrenoreceptor antagonists. Used in the treatment of benign prostatic hypertrophy.
Presentation/Packing
Form
Harnal OCAS tab 0.4 mg
Packing/Price
30's
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