Humalog Mix25/Humalog Mix50 100 units/ml KwikPen, suspension for injection is a white, sterile suspension and contains 100 units of insulin lispro in each millilitre (100 units/ml) suspension for injection. 25% and 50% of the insulin lispro in Humalog Mix25 and Humalog Mix50, respectively, is dissolved in water. 75% and 50% of the insulin lispro in Humalog Mix25 and Humalog Mix50, respectively, is available in a suspension together with protamine sulphate. Each Humalog Mix25/Humalog Mix50 KwikPen contains 300 units (3 millilitres). The Humalog Mix25/Humalog Mix50 in the KwikPen is the same as the Humalog Mix25/Humalog Mix50, which comes in separate cartridges. The KwikPen simply has a built-in cartridge. When the KwikPen is empty, it cannot be used again.
The active substance is insulin lispro. Insulin lispro is made in the laboratory by a 'recombinant DNA technology' process. It is a changed form of human insulin and so is different from other human and animal insulins. Insulin lispro is closely related to human insulin, which is a natural hormone made by the pancreas.
Excipients/Inactive Ingredients: Protamine sulphate, m-cresol, phenol, glycerol, dibasic sodium phosphate 7H2O, zinc oxide and water for injection. Sodium hydroxide or hydrochloric acid may have been used to adjust the acidity.