Humulin N/Humulin R

Humulin N/Humulin R

insulin isophane, human

Manufacturer:

Eli Lilly

Distributor:

Zuellig
/
Agencia Lei Va Hong
Concise Prescribing Info
Contents
Humulin N Human insulin (recombinant DNA origin) isophane susp. Humulin R Regular human insulin (recombinant DNA origin)
Indications/Uses
Treatment of patients w/ DM who require insulin for the maintenance of glucose homeostasis.
Dosage/Direction for Use
Contraindications
Hypersensitivity. Hypoglycaemia. Under no circumstances should any Humulin formulation other than Humulin R be given IV.
Special Precautions
Transferring from another type or brand of insulin or switching from animal insulin to human insulin. Conditions which may make the early warning symptoms of hypoglycaemia less pronounced including long-duration diabetes, diabetic nerve disease or under treatment of β-blockers. Formation of Ab. Patient w/ diseases of adrenal, pituitary or thyroid glands; renal or hepatic impairment; illness or emotional distress. Observe signs & symptoms of heart failure, wt gain & oedema if therapy is in combination w/ pioglitazone, especially in patients w/ risk factors for development of cardiac heart failure. May impair ability to drive or operate machinery. Pregnancy & lactation.
Adverse Reactions
Common: Hypoglycaemia, local allergy (redness, swelling & itching at the site of insulin inj); oedema. Rare: Systemic allergy, lipodystrophy.
Drug Interactions
Insulin requirements may be increased w/ drugs w/ hyperglycaemic activity eg, glucocorticoids, thyroid hormones, growth hormone, danazol, β2-sympathomimetics (eg, ritodrine, salbutamol, terbutaline), thiazides. Insulin requirements may be reduced w/ drugs w/ hypoglycaemic activity eg, oral hypoglycaemics, salicylates (eg, ASA), certain antidepressants (MAOIs), certain ACEIs (captopril, enalapril), angiotensin II receptor blockers, non-selective β-blocking agents & alcohol. Somatostatin analogues (octreotide, lanreotide) may both decrease or increase insulin dose requirements.
MIMS Class
Insulin Preparations
ATC Classification
A10AC01 - insulin (human) ; Belongs to the class of intermediate-acting insulins and analogues. Used in the treatment of diabetes.
A10AB01 - insulin (human) ; Belongs to the class of fast-acting insulins and analogues. Used in the treatment of diabetes.
Presentation/Packing
Form
Humulin N susp for inj 100 IU/mL
Packing/Price
(cartridge) 3 mL x 5 × 1's; (KwikPen) 3 mL x 5 × 1's; (vial) 10 mL x 1's
/hongkong/image/info/humulin n susp for inj 100 iu-ml/100 iu-ml x 10 ml?id=f94677e2-d818-4882-bc56-9fab010a4b1a
/hongkong/image/info/humulin n susp for inj 100 iu-ml/100 iu-ml x 3 ml?id=348c6216-721f-4699-a62e-9fab010a3362
Form
Humulin R susp for inj 100 IU/mL
Packing/Price
(cartridge) 3 mL x 5 × 1's; (vial) 10 mL x 1's
/hongkong/image/info/humulin r susp for inj 100 iu-ml/100 iu-ml x 10 ml?id=b8bcd2de-2514-43a5-b561-a5af011b1df2
/hongkong/image/info/humulin r susp for inj 100 iu-ml/100 iu-ml x 3 ml?id=ded88943-c18d-4c19-8904-a5af011b1df2
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