Hydrocortisone + Fusidic acid


Generic Medicine Info
Indications and Dosage
Topical/Cutaneous
Mild to moderately severe atopic dermatitis with secondary bacterial infections
Adult: Available preparation:
Each cream/ointment contains hydrocortisone 1% and fusidic acid 2%

Apply thinly onto affected area(s) bid until there is improvement. Usual treatment duration: 2 weeks.
Child: >3 years Same as adult dose.
Contraindications
Hypersensitivity to fusidic acid and its salts. Bacterial infections caused by non-susceptible organisms, fungal infections, skin manifestations due to tuberculosis, syphilis, perioral dermatitis and rosacea.
Special Precautions
Not to be used in or near the eye(s) as it may cause conjunctival irritation; may also increase the risk of increased intraocular pressure, glaucoma and cataract. Sufficient dermal absorption may occur under occlusive dressing leading to adrenal suppression and other systemic effects. May mask hypersensitivity reactions. Not to be used for >14 days in the absence of any clinical improvement. Pregnancy and lactation.
Adverse Reactions
Dryness, itching, burning, local irritation, transient stinging, striae, skin atrophy. Pigmentation changes, hypertrichosis and telangiectasia may occur. Acne rosacea or perioral dermatitis may occur if used on the face.
Action
Description: Hydrocortisone is a corticosteroid that has anti-inflammatory, antipruritic and vasoconstrictive effects. Fusidic acid has antibacterial action that results from the inhibition of bacterial protein synthesis; it is mainly active towards the gram-positive organisms especially Staph aureus.
Pharmacokinetics:
Absorption: Hydrocortisone: Dermal absorption accounts for about 1-5% of the applied amount. Fusidic acid: About 2% of the amount that is applied topically will penetrate intact skin.
Storage
Store at 15-30°C.
Disclaimer: This information is independently developed by MIMS based on Hydrocortisone + Fusidic acid from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
  • Foban Hydro
  • Fusidate H
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $768 a year.
Sign up for free
Already a member? Sign in