Imojev Description

vaccine, japanese encephalitis




Four Star
Full Prescribing Info
IMOJEV is a monovalent, live attenuated viral vaccine. The virus was obtained via recombinant DNA technology. It is based on the 17D-204 yellow fever vaccine virus in which two genes have been replaced by the corresponding genes from Japanese encephalitis (JE) virus. These are the premembrane (prM) and envelope (E) coding sequences of the SA14-14-2 live attenuated JE vaccine virus. The immunising antigens are the prM and E proteins from the SA14-14-2 vaccine virus
After reconstitution: Active ingredients: Live, attenuated, recombinant Japanese encephalitis virus*: 4.0 - 5.8 log PFU**
* Propagated in Vero cells
** Plaque Forming Unit
Excipients/Inactive Ingredients: Mannitol, Lactose, Glutamic acid, Potassium hydroxide, Histidine, Human Serum Albumin, Sodium chloride, Water for injections.
No adjuvant or antimicrobial preservative is added.
The powder is a white to creamy white homogeneous cake which might be retracted from the sides of the vial. The diluent is a clear solution. After reconstitution, IMOJEV is a colourless to amber suspension.
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