NSAIDs are contraindicated in patients who have previously shown hypersensitivity reactions (eg asthma, rhinitis, angioedema or urticaria) in response to ibuprofen, aspirin, or other non-steroidal anti-inflammatory drugs.
Hypersensitivity to Indomethacin or to any of the excipients.
Severe heart failure, hepatic failure and renal failure (see Precautions).
Not to be used in patients who have nasal polyps.
During the last trimester of pregnancy (see Use in Pregnancy & Lactation).
Safety in children has not been established.
Active, or history of recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding).
History of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy.
For the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.