Intestinal tract disease, history of bronchus asthma to suffer bronchospasm, impaired renal function, HTN, cardiac insufficiency, alimentary ulcer & haemophilia or other blood diseases eg, embolism & abnormal platelet function. Discontinue on GI bleeding, hepatic or renal function failure, ophth or auditory disfunction or blood count abnormity. May cause headache, vomiting, tiredness & hypopiesia when taken excessively. Pregnancy & lactation. Infants <6 mth.