Special precautions for disposal and other handling: Upon storage, a clear liquid and white deposit may be observed in the pre-filled syringe containing the DTPa-HBV-IPV suspension. This is a normal observation.
The pre-filled syringe should be well shaken in order to obtain a homogeneous turbid white suspension.
The vaccine is reconstituted by adding the entire contents of the pre-filled syringe to the vial containing the powder. The mixture should be well shaken until the powder is completely dissolved prior to administration.
The reconstituted vaccine appears as a slightly more cloudy suspension than the liquid component alone. This is a normal observation.
The vaccine suspension should be inspected visually before and after reconstitution for any foreign particulate matter and/or abnormal physical appearance. If either is observed, discard the vaccine.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
Specific instructions for the pre-filled syringe with a luer lock adaptor PRTC): 1. Hold the syringe barrel in one hand (avoid holding the syringe plunger), unscrew the syringe cap by twisting it anticlockwise.
2. To attach the needle to the syringe, twist the needle clockwise into the syringe until it lock.
3. Remove the needle protector, which on occasion can be a little stiff.
4. Administer the vaccine.
Incompatibilities: In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.