Use only after Invega Sustenna (1-mth paliperidone palmitate inj) has been established as adequate treatment for at least 4 mth. To establish consistent maintenance dose, the last 2 doses of Invega Sustenna should be the same dosage strength before starting Invega Trinza. Initiate Invega Trinza when the next 1-mth paliperidone palmitate dose is scheduled w/ an Invega Trinza dose based on the previous 1-mth inj dose, using the equivalent 3.5-fold higher dose (eg, if last dose of Invega Sustenna is 50 mg, initiate Invega Trinza at 175 mg dose; if last dose of Invega Sustenna is 75 mg, initiate Invega Trinza at 263 mg dose; if last dose of Invega Sustenna is 100 mg, initiate Invega Trinza at 350 mg dose; if last dose of Invega Sustenna is 150 mg, initiate Invega Trinza at 525 mg dose). Invega Trinza may be administered up to 7 days before or after the mthly time point of the next scheduled paliperidone palmitate 1-mth dose. Following initial Invega Trinza dose, administer Invega Trinza every 3 mth. Adjust dose every 3 mth, if necessary, in increments w/in the range of 175-525 mg.