Lexapro樂思保

Lexapro

escitalopram

Manufacturer:

Lundbeck

Distributor:

DKSH
/
Four Star
Concise Prescribing Info
Contents
Escitalopram
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Major depressive episodes 10 mg once daily. Panic disorder w/ or w/o agoraphobia Initially 5 mg on the 1st wk. Then increase dose to 10 mg daily. Social anxiety disorder 10 mg once daily. Dose may be decreased to 5 mg. Generalised anxiety disorder 10 mg once daily. Obsessive compulsive disorder Initially 10 mg once daily. Max (for all indications): 20 mg daily. Elderly >65 yr Initially ½ the usual recommended dose. Consider lower max dose. Reduced renal function Adjust dose. Reduced hepatic function/poor CYP2C19 metabolisers Initially 5 mg daily for the first 2 wk. Max: 10 mg daily.
Administration
May be taken with or without food.
Contraindications
Concomitant treatment w/ nonselective, irreversible MAOI. Childn <18 yr.
Special Precautions
Paradoxical anxiety, unstable epilepsy, history of mania/hypomania, diabetes, suicide/suicidal ideation, patients at risk of developing hyponatraemia, concomitant use of oral anticoagulants, drugs affecting platelet function, patients w/ bleeding tendencies, concurrent administration w/ electroconvulsive therapy, St. John's wort, CHD. Discontinue if patient develops serotonin syndrome. Avoid abrupt w/drawal esp during pregnancy. Lactation.
Adverse Reactions
Decreased appetite or libido, anorgasmia (women), insomnia, somnolence, dizziness, taste disturbance, sleep disorder, sinusitis, yawning, nausea, diarrhoea, constipation, increased sweating, ejaculation disorder, impotence, fatigue, pyrexia.
Drug Interactions
MAOI, selegiline, serotonergic drugs (eg, tramadol, sumatriptan & other triptans), drugs which lower the seizure threshold, lithium, tryptophan, St. John's wort, oral anticoagulants, alcohol. CYP2C19 inhibitors (eg, omeprazole, esomeprazole, fluoxetine, fluvoxamine, lansoprazole, ticlopidine), cimetidine, CYP2D6 inhibitors eg, flecainide, propafenone & metoprolol, other CNS-acting drugs.
MIMS Class
ATC Classification
N06AB10 - escitalopram ; Belongs to the class of selective serotonin reuptake inhibitors. Used in the management of depression.
Presentation/Packing
Form
Lexapro tab 10 mg
Packing/Price
28's
Form
Lexapro tab 20 mg
Packing/Price
28's
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