Lutathera Overdosage




Global Medical Solutions
Full Prescribing Info
Overdose is unlikely with Lutathera as this medicinal product is supplied as a "single dose" and "ready to use" product containing a predefined amount of radioactivity. In the case of overdose, an increase in the frequency of the adverse reactions related to radiotoxicity is expected.
In the event of administration of a radiation overdose with Lutathera, the absorbed dose to the patient should be reduced where possible by increasing the elimination of the radionuclide from the body by frequent micturition or by forced diuresis and frequent bladder voiding during the first 48 hours after infusion. It is helpful to estimate the effective dose that was applied.
The following checking should be carried out every week, for the next 10 weeks: Hematologic monitoring: white blood cells, platelets, and haemoglobin.
Blood chemistry monitoring: serum creatinine and glycaemia.
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